CCL2 and Hepatic fibrosis: Similar results were obtained by measuring the expression of the pro-inflammatory cytokines playing important roles in the process of fibrosis, including Interleukin-6 (Il-6), Interferon-gamma (Ifn-γ), and monocyte chemotactic protein 1 (Mcp1) overtime during the treatment of the liver fibrosis through qPCR and Western blot (Fig. 4a, f and Additional file 1: Fig. S10).