AEs of Grade 3–4 severity were reported for four cipargamin patients (Grade 3 leukopaenia, Grade 4 thrombocytopaenia, Grade 3 ALT increase, Grade 3 hypomagnesemia) and two artemether–lumefantrine patients (Grade 3 hyperbilirubinaemia and Grade 3 gamma-glutamyl transpeptidase; Grade 3 thrombocytopaenia). The gene discussed is GPT; the disease is Hypomagnesemia.