The results showed that expressions of CCR7, CXCR3, CXCR5, CCL5, CXCR4, CCL19, CCL21, CXCL13, CXCR6, SAA1, S1PR4, PONC were significantly elevated in pancreatic tumor tissue from the TCGA dataset compared with normal tissues from the GTEx dataset. This evidence concerns the gene S1PR4 and pancreatic neoplasm.