The result showed that CCR7, CXCR3, CXCR4, CXCR5, CXCR6, CXCL13, CCL5, CCL19, CCL21, SAA1, S1PR4, PONC were significantly elevated in pancreatic tumor tissue from TCGA datasets compared with normal tissues from GTEx datasets. The gene discussed is CXCR6; the disease is pancreatic neoplasm.