Specifically, it has been reported that XIST promoted lung cancer cell activities by upregulating BCL-2 (Fig. 2D), iASSP (Fig. 2E), LARP1 (Fig. 2F), Notch1 (Fig. 2G), RING1 (Fig. 2H), SOD2 (Fig. 2I), CDK8 (Fig. 2J), CBLL1 (Fig. 2K), MDM2 (Fig. 2L), and PAX6 (Fig. 2M) via regulation of miR-449a (Zhang et al. 2017b), miR-140 (Tang et al. 2017), miR-374a (Xu et al. 2017), miR-137 (Wang et al. 2018), miR-744 (Wang et al. 2019), miR-335 (Liu et al. 2019), miR-16 (Zhou et al. 2019), miR-212-3p (Qiu et al. 2019), miR-363-3p (Rong et al. 2020), and miR-142-5p (Jiang et al. 2020), respectively. The gene discussed is XIST; the disease is lung cancer.