It was further demonstrated that XIST promoted pancreatic cancer cell progression through upregulating EGFR (Fig. 1S), iASSP (Fig. 1T), YAP (Fig. 1U), ZEB1 (Fig. 1V), TGF-β2 (Fig. 1W), and Notch1 (Fig. 1X) by modulating miR-133a (Wei et al. 2017), miR-140/miR-124 (Liang et al. 2017), miR-34a (Zou et al. 2020), miR-429 (Shen et al. 2019), miR-141-3p (Sun and Zhang 2019), and miR-137 (Liu et al. 2020), respectively. This evidence concerns the gene XIST and familial pancreatic carcinoma.