Furthermore, neovascularization with overexpression of angiogenic factors such as platelet‐derived endothelial cell growth factor or vascular endothelial growth factor in the bladder mucosa has been identified as an important mechanism leading to glomerulations in non‐Hunner‐type IC/BPS.19, 20, 21. This evidence concerns the gene VEGFA and Bartsocas-Papas syndrome 1.