Allelic differences in CDKAL1 (Cdk5 regulatory associated protein 1-like 1), CDKN2A-2B (cyclin-dependent kinase inhibitor 2A), HHEX (hematopoietically expressed homeobox), IGFT2BP2 (Insulin Like Growth Factor Binding Protein 2), SLC30A8 (Solute Carrier Family 30 Member 8), and TCF7L2 (Transcription Factor 7 Like 2) conferred an increased risk of GDM [40]. The gene discussed is IGFBP2; the disease is gestational diabetes.