Specifically, numerous studies have indicated that targeting OTUB1 could induce myeloma cell apoptosis [31,32], and the anti-bacterial and anti-viral nanchangmycin has been shown to suppress OTUB1 and thus promote myeloma cell apoptosis [33], future efforts can be performed to determine the effects of nanchangmycin on glioma treatment. Here, OTUB1 is linked to central nervous system cancer.