CD274 and cancer: Prior to that, researchers have demonstrated that combined anti‐PD‐L1 with amplified sonosensitizers of SDT induced immune cancer response, which killed tumor and prevented metastasis.[184] These methods represent a combinatorial proof‐of‐concept based on non‐invasive tumor immunotherapy.[185] In addition, the combination of CDT and SDT eliminated cancer cells, inhibited the expression of metastatic protein, and induced immune response by releasing TAAs.