APOE and Alzheimer disease: Interestingly, PART is not associated with the APOE ε4 allele but rather with the APOE ε2 allele [19], which is noteworthy because the APOE ε4 allele is commonly known as the strongest genetic risk factor for sporadic late‐onset AD [20], whereas APOE ε2 might have more of a protective role [21].