Interestingly, significant differences in the phosphorylation status of the autophosphorylation sites of EGFR Y1068 and Y1173 were noted in the tumor (P = 0.01 and P = 0.03, respectively) but not the adjacent normal colon tissue (P = 0.09 and P = 0.10, respectively) of Anthos treated compared to control animals. This evidence concerns the gene EGFR and neoplasm.