The correlation between BACE1-AS and TME in GBM was the most significant, with BACE1-AS having the highest correlation coefficients with immune scores (R = −0.53, P < 0.05), stromal scores (R = −0.51, P < 0.05), and estimate scores (R = −0.54, P < 0.05). The gene discussed is BACE1; the disease is glioblastoma.