BACE1-AS expression mainly affected pathways including complement and coagulation cascades, RRAR signaling pathway, intestinal immune network for immunoglobulin A (IgA) production, cancer pathways, autophagy regulation, cytokine-cytokine receptor interaction, and antigen processing and presentation, which are mainly related to tumorigenesis and immune activity (Figure 9). The gene discussed is BACE1; the disease is cancer.