Our analyses show that the expressions of CALU and PALLD were significantly negative correlated with the abundances of DC, NK CD56dim cells, T cells, Tfh, Tgd and Th2 cells, and Tcm, suggesting that CALU and PALLD may regulate HF via immune-related pathways mediated by the infiltration of these immune cells. Here, ABCA1 is linked to hydrops fetalis.