Although the differential expression of COX5A (Cytochrome C Oxidase Subunit 5A) and ACSBG1 (Acyl-CoA Synthetase Bubblegum Family Member 1) suggested IHD selectivity, with their expressions significantly correlating with the SYNTAX scores (ANOVA p = 0.012 and p = 0.030; FDR 0.060 and 0.085, respectively), this difference did not emerge in the DEG comparison between the IHD compared with non-IHD groups. This evidence concerns the gene COX5A and myocardial ischemia.