NPC1L1 and coronary artery disorder: Polisencki et al. (10) investigated the SNPs of NPC1L1 in elderly patients (mean age of 75 ± 3 years) with CHD, data indicated that variation in the NPC1L1 gene is associated with plasma total and LDL-C levels and the risk of CHD events (HR: 1.50–1.67; P < 0.02).