CHGA and carcinoid tumor: Immunoreactivity for chromogranin A, synaptophysin, TTF-1, and pan-cytokeratins (AE1-3 clone) was observed in carcinoid component, while glandular component was positive only for TTF-1 and cytokeratins; cytokeratin 7 was selectively expressed in the adenocarcinomatous component (Figure 3).