Other researchers observed that feeding STZ-T1DM pregnant rats with ω-6/ω-3 ratio 0.49, induced beneficial effects such as a significant reduction of glucose levels, upregulated IL-4 mRNA expression in the spleen, and IL-10 mRNA in the pancreas, and spleen and significantly increased serum IL-4 concentrations. Here, IL4 is linked to type 1 diabetes mellitus.