KLRK1 and neoplasm: Nevertheless, in this study, we did not observe an increase in the secretion of NKG2D ligand MICA/B, even though SCI-101 treatment significantly increased the expression of NKG2D ligands, depicting the potential safety of SCI-101 in terms of antigen shedding and tumor escape as well as efficiency in triggering enhanced NK cell–mediated anti-tumor responses.