Zinc finger CCCH-type containing, antiviral 1 (ZC3HAV1), also known as zinc-finger antiviral protein (ZAP), has been shown to limit the replication of certain viruses, thereby preventing virus-related cancers such as liver cancer (Mao et al., 2013) and leukemia (Gao et al., 2002). This evidence concerns the gene ZC3HAV1 and cancer.