Carbamazepine-induced SJS/TEN manifested a very strong association with the HLA-B*15:02 allele in Taiwanese Han Chinese patients (14), and the HLA-A*31:01 allele was strongly associated with carbamazepine-induced SJS/TEN in Japanese- (15) and European patients (16), the HLA-B*57:01 allele was associated with carbamazepine-induced SJS/TEN in European patients (17). This evidence concerns the gene HLA-B and toxic epidermal necrolysis.