For instance, lncRNA TINCR promoted trastuzumab resistance and EMT through facilitating the release of HER-2 and upregulating Snail-1 in breast cancer (Dong et al., 2019); LINC00336, a nuclear lncRNA, served as an endogenous sponge of microRNA 6,852 to inhibit ferroptosis (Wang et al., 2019b). Here, ERBB2 is linked to breast cancer.