The role of FGF10 signaling in human lung development and CDH is understudied and likely has different effects than in the mouse (Danopoulos et al., 2019a; Danopoulos et al., 2019b), but this growth factor has been shown to induce the secretion of fluid into the lumen of the human fetal lung (Graeff et al., 1999) and is found at reduced levels within the amniotic fluid of fetuses with CDH (Candilera et al., 2016). This evidence concerns the gene FGF10 and congenital diaphragmatic hernia.