LAMB2 and neoplasm: It is composed of non-malignant cells of tumor-like cancer-associated fibroblasts (CAFs) (Raghu et al., 2016; Tang et al., 2016; Lee et al., 2018; Liu et al., 2019; Monteran and Erez, 2019; Wang et al., 2019; Yavuz et al., 2019), tumor-associated macrophages (TAMs) (Qian et al., 2009; Noy and Pollard, 2014; Larionova et al., 2019; Lin et al., 2019), tumor-associated neutrophils (TANs), mesenchymal stem cells and extracellular matrix (ECM) with fibrous structural proteins (e.g., collagen and elastin), fibrous adhesive proteins (e.g., laminin and fibronectin), and proteoglycans.