* “Sensitivity of NSCLC cells to CDDP is negatively associated with Nrf2 pathway activation”* “Erastin and sorafenib effectively induce ferroptosis in CDDP resistance cells by inhibiting the Nrf2/xCT pathway”* “Erastin/sorafenib restrains in vivo tumour growth in nude mice xenograft models”. Here, NFE2L2 is linked to non-small cell lung carcinoma.