TNF and cancer: * “Attenuated self-renewal ability of cancer and downregulated angiogenesis-related genes and caused lipid peroxidation, increased ROS, and ferroptosis.”* “Inhibited NRF2 activity and lung metastases in vivo.”* “ZVI-NP treatment promoted the M1 polarization induction-derived overexpression of TNF-α, while attenuated the expression of the M2 polarization gene DC-SIGN”* “ZVI-NP modulates immune cell profile in mouse model in vivo”.