ERBB2 and gastric cancer: In ToGA (Trastuzumab for Gastric Cancer) trial, trastuzumab plus chemotherapy showed significantly longer OS (18.6 versus 17.1 months; HR 0.74 [95% CI 0.60-0.91]; P=0.0046) than the chemotherapy alone for HER2-positive gastric or gastroesophageal junction cancer.