Studies have demonstrated the relationship between circRNAs and macrophages—for example, circASAP1 can act as a competing endogenous RNA (ceRNA) of miR-326 and miR-532-5p to mediate TAM infiltration, and circRNA-CDR1as may be crucial for tumor tissue immunity and cell penetration, such as CD8+ T cells, activated natural killer (NK) cells, and M2 macrophages (116). Here, LINC00632 is linked to neoplasm.