Based our previous RNA-sequencing data from 10 pairs of primary HCC tissues with extrahepatic metastasis (EHMH) and 10 pairs of metastasis-free HCC tissues (MFH), ribosomal protein L23 (RPL23) is extremely upregulated in HCC tissues, especially in those tissues with extrahepatic metastasis (EHMH). Here, RPL23 is linked to hepatocellular carcinoma.