Their findings are in line with the high frequency of splicing factor mutations in MDS such as SF3B1 and SRSF2 which impairs erythroid cell maturation (49) or skew megakaryo‐erythroid differentiation toward megakaryocytes respectively (50), suggesting the possible role of alternative splicing in erythroid lineage commitment. This evidence concerns the gene SRSF2 and myelodysplastic syndrome.