After identification of SEPT6_TRIM33 fusion genes, mutated TP53 and Hippo pathways as factors significantly associated with prognosis of B-cell lymphomas, multivariable Cox analyses adjusted by clinic covariates [age, gender, BMI, smoking history, drinking status and treatment (R-CHOP or R-CHOP-like regimes vs others)] were conducted. This evidence concerns the gene DDIT3 and B-cell non-Hodgkin lymphoma.