One study from China conducted a genetic analysis of 273 patients with BRCA1/2-negative FBC and identified four previously unknown amino acid substitution variants in the RAD51C gene, the 4C>G (R2G) located in exon 1, 635G>A (R212H), and 644A>G (D215G) in exon 4, and 882G>C (Q294H) in exon 6. The gene discussed is BRCA1; the disease is complete blood cell count.