A previous study determined that TET1 acted as a tumor suppressor in nasopharyngeal carcinoma via antagonizing Wnt/β-catenin pathway [14].Corresponding with previous research, our work identified that downregulation of TET1 could increase the expression of key proteins of Wnt/β-catenin including β-catenin and phosphorylated GSK3β and the underlying targets of Wnt pathway such as cyclinD1 and c-myc (Figures 6(a)–6(c)). This evidence concerns the gene MYC and nasopharyngeal carcinoma.