CRP levels at any time point were not predictive of subsequent follow-up PSA. One would expect that as the cancer regresses (as measured by a declining PSA), so would the inflammatory response, and thus the CRP, which was not seen. This was true not only after the radiation, but also for those that received initial androgen ablation where only PSA significantly changed from pre-AA to pre-RT in both the no-surgery and surgery subsets (p<0.0001 and 0.0156, respectively). Here, KLK3 is linked to cancer.