DM is associated with increased concentration of serum inflammatory markers such as C-reactive protein (CRP), soluble suppression of tumorgenesis-2 (sST2), galectin-3, C-terminal propeptide of procollagen type I (PICP), N-terminal propeptide of procollagen type III (PIIINP), matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of matrix proteinase-1 (TIMP-1) [24]. Here, MMP9 is linked to diabetes mellitus.