GLA and Fabry disease: The majority of cases are reported in Caucasians, and most patients who present with symptoms are male [2]. There are different types of FD mutations on the alpha-galactosidase (GAL) gene which causes the disease, including point mutations (83.4%), missense mutations (50%), nonsense mutations (29.2%), frameshift mutations (16.6%), and splicing (4.2%) [1].