HES1 and gastric adenocarcinoma: Four genes (NOTCH1, NOTCH2, NOTCH3, and HEY1) were found to be significantly associated with overall survival in STAD, whereas the remaining 7 NOTCH genes (NOTCH4, DLL1, DLL3, DLL4, JAG1, JAG2, and HES1) did not display a prognostic value for overall survival (Figure 2).