Interestingly, prognostic model based on epigenetic regulation was constructed to predict patient prognosis, such as a prognostic model based on nine ferroptosis-related genes (ALOX15, CISD1, CS, GCLC, GPX4, SLC7A11, EMC2, G6PD, and ACSF2) that could predict the prognosis of breast cancer [45]. The gene discussed is GCLC; the disease is breast carcinoma.