In TCGA-SARC cohort, the infiltration degrees of CD8+ T cell, dendritic cell (DC), immature DC (iDC), macrophage, mast cell, neutrophil, natural killer (NK) cell, plasmacytoid DC (pDC), T helper (Th) cell, T follicular helper (Tfh) cell, Th1 cell, Th2 cell, tumour-infiltrating lymphocyte (TIL) and regulatory T cell (Treg) were significantly lower in the high pyroptosis-related risk group (p < 0.05, Figure 7A). The gene discussed is CD8A; the disease is neoplasm.