TNFSF14 (TNF superfamily member 14) is a member of the tumor necrosis factor (TNF) ligand family, encodes by TNFSF14. The expression of TNFSF14 within tumors has profound effects on host immune responses against tumors and the remodeling of the tumor microenvironment (Skeate et al., 2020). The gene discussed is TNF; the disease is neoplasm.