TET2 and diffuse large B-cell lymphoma: In the studies of Lacy et al. (2020) and Wright et al. (2020), the significance of TET2/SGK1 as a classification factor was mentioned, but in the two cohorts of this study, these two mutations are completely independent (TET2/SGK1 co-mutant only occurred in one patient in both cohorts), which suggests that the mutation lineages of RRDLBCL and de novo DLBCL are still different.