NLRP3 and Parkinson disease: Our current results show that NBP not only inhibited the activation of the NLRP3 inflammasome and reduced the level of inflammatory cytokines, but also reduced the abnormal accumulation and phosphorylation of α-Syn in animal and cell models of PD by ameliorating mitochondrial impairments, thus reducing the pathological changes in α-Syn, which in turn also reduced the inflammatory reaction to some extent.