A phase I/II trial using the Ad5[E1-, e2b-]-CEA (6D) vaccine for advanced CRC reported a median survival time for the 32 patients included in the study of 11 months, and the Ad5 [E1-, e2b -] - CEA (6D) vaccine was well tolerated and induced an immune response (286). The gene discussed is CEACAM5; the disease is colorectal carcinoma.