Other studies examining Chlamydia muridarum specific Th1 and Th17 T cells, either transgenically generated or induced by vaccine, also showed that Th1/Th17 T cells that express multiple cytokines (IFNγ, IL-2, TNFα and or IL-17) although the local post infection development of these cells was not analysed in these studies (25–27). This evidence concerns the gene TNF and infection.