a. Healthy (birth)Low cord blood type I IFN responses associated with recurrent wheeze during 5 years of life (15) b. Acute disease (severe bronchiolitis)High IFN-α transcript levels in nasopharyngeal aspirates of infants with RSV-bronchiolitis associated with asthma diagnosis at 5 years old (16). Here, IFNA1 is linked to bronchiolitis.