Cluster 1 contained a total of seven variables representing the inflammation (IL-6, IL-1RA, CRP, and PCT-M), renal function (UREA and CRE), and hepatic function (ALT), which indicated the potential association between inflammation response, alanine aminotransferase, and disorder of renal function in the progression of COVID-19. The gene discussed is GPT; the disease is COVID-19.