In univariate analysis, significant difference was found in such baseline variables as GCS score at ICU admission (p< 0.001), CRP score at ICU admission (p< 0.001), sex (p< 0.001), hypertension (p= 0.039), and smoking status (p= 0.002) between SAP and non-SAP (Table 1). This evidence concerns the gene CRP and hypertensive disorder.