As a novel target for autoimmune uveitis, IL-6 impacts the differentiation and stimulation of Th17 cells with TGF-β and IL-23, while considering that IL-1β is necessary for the production and regulation of IL-6, the inflammasome might be highly involved in the development of uveitis (Rose-John, 2012). The gene discussed is IL1B; the disease is autoimmune uveitis.