ICAM1 and endothelial dysfunction: Aggravated endothelial inflammation, which is characterized by overexpressed cytokines and adhesion molecules such as intercellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1), and selectins (Konukoglu and Uzun, 2017), is an important pathological process in endothelial dysfunction.