Their results suggested that gingerol also had a good binding affinity with all these target enzymes, especially Cathepsin K. Their further performed studies indicated that gingerol could form hydrogen bonding with Asn18, Gln19, His162, Trp184, and Trp188 amino acid residues of Cathepsin K. It also has the potential to form hydrogen bonding with Thr199, Leu272, and Leu287 amino acid residues of the COVID-19 main protease. This evidence concerns the gene CTSK and COVID-19.