MITF and neoplasm: For example, Gilot et al. has demonstrated that the sequestration of miR-16 by the mRNA of melanocyte specifically-expressed TYRP1 can promote tumor growth by relieving the suppression of downstream tumor-promoting factors like RAB17, highlighting miRNA displacement as a promising therapeutic approach.187 The crosstalk between melanocytic lineage-specific factor and non-coding RNA is further extended by the investigation conducted by Leucci et al., which demonstrates that recently annotated lncRNA SAMMSON is co-amplified with MITF and plays an oncogenic role.