In contrast, STZ-induced diabetes significantly reduced levels of colocalization between glucagon and Lamp2A (PCC 0.14 ± 0.03; p < .001) and also between Stmn2 and Lamp2A (PCC 0.15 ± 0.03; p < .001) (Figure 4G). The gene discussed is STMN2; the disease is diabetes mellitus.