HEMGN and aplastic anemia: Third, microarray analysis reveal that knockdown of Hemgn in human CD34+ cells increases the expression of IFN‐γ‐inducible genes.[17] Fourth, in a global transcriptome analysis of CD34+ cells from severe aplastic anemia patients, which the function of HSPCs is impaired by intrinsic IFN‐γ inhibition, revealed significant down‐regulation of Hemgn.