Hemogen (Hemgn), homologous to human erythroid differentiation‐associated gene (EDAG) and rat RP59,[7, 8] is a vertebrate transcriptional regulator that performs important functions in hematopoietic and testicular development and might contribute to neoplasia.[9, 10] In hematopoietic cells, Hemgn is mainly expressed in active hematopoietic sites and downregulated during blood cell differentiation process. Here, HEMGN is linked to neoplasm.