Third, microarray analysis reveal that knockdown of Hemgn in human CD34+ cells increases the expression of IFN‐γ‐inducible genes.[17] Fourth, in a global transcriptome analysis of CD34+ cells from severe aplastic anemia patients, which the function of HSPCs is impaired by intrinsic IFN‐γ inhibition, revealed significant down‐regulation of Hemgn. This evidence concerns the gene CD34 and aplastic anemia.